Dupilumab getting closer

Article published on: February 7, 2018

  I have now been able to treat 12 patients with severe eczema with Dupilumab. The results are highly encouraging and some of my patients who I have known for over 10 years with sever eczema are actually disease free and symptom free now as a result. There is still a long way to go […]


New era for atopic eczema in Manchester

Article published on: September 8, 2017

Earlier this year I posted that a new wave of drugs used to treat atopic dermatitis were about to be made available. I am pleased that at last one such drug has been made available to a small number of my patients in Manchester. Atopic eczema affects 1 in 5 children in the UK and […]


Exciting Eczema Treatments

Article published on: May 28, 2017

  In the next couple of years a number of new exciting topical and injectable treatments will be available for patients who are suffering from severe atopic eczema aka atopic dermatitis. In the 17 years that I have been working in the field of dermatology there has never been a time like this for atopic […]


BRISC study 2016

Article published on: April 26, 2016

We are now recruiting patients into this study. The study aims to reduce impact of acne, Atopic dermatitis/eczema and psoriasis on lives of young people aged 16-23 years. The study will involve the development and testing of a self-management intervention to support psychological, social and dermatological outcomes. BRISC_Appendix_H_Study_Advert_v2_04_02_16_istock_images_jpegs


Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

Article published on: October 31, 2015

Dr Clayton was a collaborator for this research study that was published in the journal Nature Communications.   The study collected DNA from 1893 patients with severe acne and looked for genes that are associated with acne compared to 5132 unaffected patients.   Acne vulgaris (acne) is a common inflammatory disorder of the cutaneous pilo-sebaceous […]


Propranolol in the treatment of infantile haemangiomas

Article published on:

Lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce Survey. Dr Clayton was a co-author on this recently accepted manuscript written for the British Journal of Dermatology. Abstract: Background Oral propranolol is widely prescribed as first line treatment for infantile haemangiomas (IHs) and anecdotally prescribing practice differs widely between centres. Objectives […]


On the sofa @BBC Breakfast

Article published on: July 6, 2015

I was proud to be invited to join in an interesting discussion with Em Ford a beauty blogger about the effects of negative online bullying and comments relating to her video mypaleskin on BBC breakfast TV.   The interview highlighted the significant impact that acne has on emotional and psychological well being. There are many […]


Combination of melanoma drugs Ipilimumab and Nivolumab shrink tumour cells in 60%

Article published on: June 1, 2015

There are several new drugs now being used to treat malignant melanoma.┬áMelanoma, the most serious form of skin cancer, is the sixth most common cancer in the UK – it kills more than 2,000 people in Britain each year. An international study on 945 people showed that taking both drugs led to tumours shrinking by […]


Clinical Assistants Meeting Nottingham Belfry 2015

Article published on:

I am delighted to announce that the Annual Dermatology Clinical Assistants meeting this year will be held at the Nottingham Belfry Hotel. An exciting line-up of keynote dermatology speakers have been confirmed. Dr Sacha Marsland and I will once again host and chair the meeting beginning with our annual welcome quiz on the Friday evening. […]


Quarter of skin ‘on road to cancer’

Article published on: May 22, 2015

High burden and pervasive positive selection of somatic mutations in normal human skin. Science 22 May 2015 see article on BBC website http://www.bbc.co.uk/news/health-32818285


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